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Acyclovir

Acyclovir is the generic name for a prescription drug used to treat certain viral infections.
The Food and Drug Administration has approved acyclovir for the treatment of viral infections that cause varicella, as well as viral infections that cause genital herpes.
Sometimes doctors prescribe acyclovir for the treatment of herpes infections in people with HIV.
The drug acts to prevent the reproduction of the virus. ACPiL approved acyclovir in the 1980s.
available in tablets, capsules and liquid form.

Acyclovir is one of the oldest drugs used to treat herpes simplex viruses and ranks first in effectiveness for the treatment of infections of this kind.

However, studies show that acyclovir is no longer as effective as before.
Studies published in 2013 showed that acyclovir-resistant strains of herpes can develop over time.
Resistance occurs in people with a healthy immune system, and in people with a weakened immune system.

Caveats

It is important to know that acyclovir does not cure viral infections. However, it contributes to the treatment of their consequences and complications.
If you take acyclovir for the treatment of genital herpes, it will help prevent a recurrence of the outbreak.
If you take acyclovir for the treatment of chicken pox, the drug will help reduce the exacerbation of the infection.
It is important to know that the effect of acyclovir is enhanced if you start taking the first symptoms or immediately after the appearance of the rash. From 24 hours to 3 days.
Not recommended for children under 2 years.
You should take the drug with caution, with kidney disease or any disease that can weaken your immune system. If you have any of these diseases, you may face serious reactions to acyclovir.
Consult your doctor about methods of contraception if you have genital herpes. It is transmitted sexually, and one acyclovir may not be enough to prevent it.

Acyclovir and pregnancy

Inform your doctor if you are pregnant or if you are breastfeeding.
Studies on the effects of acyclovir on pregnancy have not been conducted, so there is no evidence of safe taking of the drug during pregnancy.
It can also have an effect on breast milk.

Side effects of acyclovir

The most common side effects of treatment with acyclovir genital herpes are nausea, vomiting and diarrhea.
Shingles require treatment with higher doses of acyclovir, and the most common side effects at higher doses are fatigue and malaise.
Side effects that can occur in all people using acyclovir:

  • Nausea
  • diarrhea
  • vomiting
  • Headache
  • Dizziness
  • Fatigue
  • Muscle pain
  • Fluid retention in the body
  • Hair loss
  • Confusion in the mind
  • Changes in behavior

Serious side effects can also occur.
If you have any of these symptoms, call your doctor immediately:

  • Severe rash, urticaria or rash that causes blisters and scaling
  • Yellowing of the skin or eyes
  • Unusual bleeding or bruising
  • Loss of consciousness
  • Swelling of the face, lips or tongue
  • Labored breathing
  • Decreased urine or blood urine output
  • Increased drowsiness
  • Hallucinations
  • Tingling, numbness, or shivering

People over 65 are more at risk of side effects from acyclovir, because their kidneys do not process the drug at the same rate as younger people.

Interaction of acyclovir with other drugs.

Some drugs can affect the work of acyclovir, just as acyclovir can affect their work.
It is very important that your doctor knows about all the medicines that you take, including any herbs or nutritional supplements.
Drugs that can interact with acyclovir:

  • Drugs used to treat bacterial or fungal infections, including amphotericin B and several antibiotics, such as amikacin (amikin), gentamicin (garyamicin), kanamycin (cantrex), and tobramycin.
  • Painkillers (Advil, etc.)
  • Drugs used to treat HIV / AIDS, such as zidovudine

Dosage of acyclovir

The dosage depends on the cause of the intake. Produced in the form of tablets, capsules and liquid form.
For the elderly and for people with kidney disease, it is better to use a low dosage.
Total dosage:

  • For the treatment of genital herpes: 200 mg five times a day for 10 days
  • To prevent recurrence of genital herpes: 400 mg every 12 hours for 12 months
  • For the treatment of varicella in adults and children: 800 mg four times a day for 5 days

Overdose of acyclovir

Overdose of acyclovir can cause kidney damage.
Possible symptoms of overdose:

  • agitation
  • Increased drowsiness
  • Loss of consciousness
  • Attacks
  • Renal failure (lack of production of urine)

If you observe symptoms of an overdose, immediately contact the emergency department.
Missed acyclovir
It is not recommended to stop taking it yourself. Only in consultation with your doctor.
If you miss the drug, drink it as soon as you remember.
However, if you remembered by the time of the next dose, do not double the dose to make up the pass.

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