Augmentin is a trademark of a combined antibiotic drug containing amoxicillin and clavulanate potassium.
It is used to treat bacterial infections in your airways, such as sinus infection or pneumonia
Amoxicillin is an antibiotic of penicillin that kills bacteria by blocking the production of a chemical in which microbes need to create their own cell walls.
Clavulanate is a chemical that helps antibiotics overcome the resistance to antibiotics of certain bacteria.
The Food and Drug Administration (FDA) approved Augmentin in 1984. GlaxoSmithKline is one of several companies that produce it.
Augmentin can cause a severe form of diarrhea, called Clostridium difficile-associated diarrhea (CDAD). It is characterized by a loose, watery stool with a very unpleasant odor.
CDAD causes dehydration and can cause sepsis in severe cases.
Because dehydration can disrupt your sodium and potassium levels, you may have tremors, weakness, irregular heartbeats, or all three symptoms.
Augmentin, like other antibiotics of penicillin, can cause a severe, life-threatening allergic reaction known as anaphylaxis.
If you are sensitive to this, you may have trouble breathing, and the mouth, gums and throat can swell.
Do not take Augmentin if you are allergic to it or any ingredients in it.
Avoid Augmentin if you have had an allergic reaction to another antibiotic from penicillin or a beta-lactam antibacterial drug.
Talk with your doctor before taking Augmentin if you:
- You have problems with the liver or kidneys, especially if you need
- Have mononucleosis
- Have ulcerative colitis
- HIV / AIDS is sick
- Acute lymphoblastic leukemia (ALL)
- Take blood thinners, such as warfarin (Jantoven, Coumadin)
- Take Probalance (probenecid)
Augmentin and pregnancy
Most doctors believe that Augmentin can be safely taken during pregnancy.
However, talk to your doctor if you are pregnant or plan to become pregnant or breastfeed before taking this medication.
Admission Augmentin during pregnancy can reduce the level of estrogen.
Because it lowers estrogen levels, Augmentin makes birth control pills less effective.
If you are taking oral contraceptives, consider using a contraceptive reserve form.
Augmentin can be given to an infant through breast milk, although it is considered safe.
Nevertheless, talk with your doctors about the risks associated with the use of Augmentin before breastfeeding.
Additional effects of Augmentin
Common side effects of Augmentin include:
- Nausea, vomiting, or diarrhea
- Swelling of the tongue and mouth
- Blackening tongue
- Oral form of Candida infection
Serious side effects of Augmentin include:
- Clostridium difficile-associated diarrhea (CDAD) (severe form of diarrhea)
- Severe and potentially life-threatening skin diseases
- Skin irritation or inflammation
- Multiple infections simultaneously
- Blood or bone marrow disorders, such as low levels of red blood cells or leukocytes
Inform your doctor and pharmacist of all the medicines you take.
This includes drugs, vitamins and other nutritional supplements (nutritious cocktails, protein powders, etc.), herbs and drugs.
Augmentin interacts with many medicines. These include:
- Exenatide (Betta, Bidureon)
- Chloroquine (Aralen)
- Methotrexate (Rheumatrex, Trexall)
- Magnesium citrate (Citroma)
- Warfarin (Kumadin, Jantoven)
- Omeprazole (Prilosec), Esomeprazole (Nexium), Rabeprazole (Aciphex), and Dexilansoprazole (Dexilant)
- Tetracycline antibiotics, such as tetracycline or Doxycycline (Vibramycin)
- Tramadol (Ultram, Ultracet)
- Mycophenolate mofetil (Cellcept)
- Bupropion (Aplenzin, Contrave, Forfivo XL, Wellbutrin, Zyban)
Augmentin and alcohol
Since both Augmentin and alcohol can cause dizziness and drowsiness, the simultaneous application of these two components can enhance these effects.
Avoid or limit alcohol use while using Augmentin.
Augmentin and grapefruit juice
Avoid grapefruit juice by taking Augmentin.
Scientists do not know if the Augmentin liver is destroyed in the same way as grapefruit juice.
Dosage of Augmentin
Augmentin is available as a tablet or liquid. To avoid indigestion, take it with food or snacks.
Tablets contain different doses of amoxicillin. Augmentin tablets have the following dosages:
- 250 mg / 125 mg
- 500 mg / 125 mg
- 875 mg / 125 mg
Liquid Augmentin ES contains either 600 mg of amoxicillin, or 42.9 mg of clavulanate per 5 milliliters (mL), or 400 mg of amoxicillin and 57 mg of clavulanate per 5 mL.
Tablets Augmentin XR contain 1000 mg or 1 g of amoxicillin and 62.5 mg of clavulanate.
In general, you should not take more than 1200 mg of amoxicillin per kilogram of body weight per day.
Your doctor may also prescribe Augmentin syrup if you or someone you care about has problems swallowing pills.
Like all antibiotics, be sure to finish taking all the medications prescribed by your doctor, even if you are feeling better.
Augmentin and children
Your child’s doctor can prescribe Augmentin syrup, which the pharmacist will make from a powder containing amoxicillin and clavulanate.
The doctor determines the dose for the child, based on the mass of his body.
The dose of 5 ml contains the following amounts of amoxicillin and clavulanate:
- 200 mg / 28 mg
- 400 mg / 57 mg
- 125 mg / 31.25 mg
- 250 mg / 62.5 mg
Overdose with Augmentin
If you suspect an overdose, immediately contact a poison control center or an emergency room.
You can contact the Toxicology Center
The missed dose of Augmentin
If you miss a dose of Augmentin, try to drink it as soon as you remember.
If it is almost time for the next dose, skip the missed dose and take the next dose in regular time.
Do not take two doses of Augmentin at the same time.