Bicalutamide is an antiandrogen. It works in the body, preventing the action of androgens (male hormones).
Bicalutamide is used together with another hormone to treat prostate cancer.
Bicalutamide can also be used for purposes not listed in this manual.
Although bicalutamide is not used by women, this medicine can cause birth defects if the woman is exposed to it during pregnancy.
You should not use this medication if you are allergic to bicalutamide.
Use an effective contraceptive method if your sexual partner can become pregnant. Continue to use contraceptives for at least 130 days (about 19 weeks) after the last dose.
Bicalutamide should never be taken by a woman or child.
To make sure that bicalutamide is safe for you, tell your doctor if you have:
- liver disease;
- diabetes; or
- if you take a blood thinner (warfarin, coumadin, gentenes).
Bicalutamide: side effects
Obtain immediate medical attention if you have signs of an allergic reaction: shortness of breath; swelling of the face, lips, tongue, or throat.
Call your doctor right away if you have:
- chest pain or swelling;
- blood in the urine;
- fever, chills;
- sudden chest pain or discomfort, wheezing, dry cough, feeling short of breath;
- low red blood cells (anemia) – pale skin, a feeling of light dizziness or lack of air, a fast heart rate, problems with concentration of attention;
- liver problems – nausea, stomach pain, fatigue, loss of appetite, dark urine, clayey stool, jaundice (yellowing of the skin or eyes); or
- high blood sugar – increased thirst, increased urination, hunger, dry mouth, drowsiness, dry skin, blurred vision, weight loss.
Common side effects may include:
- pain in the back or stomach;
- swelling of the hands, ankles, or feet;
- increased frequency of nighttime urination;
- weakness, dizziness; or
- nausea, diarrhea, constipation.
This is not a complete list of side effects, and others may also occur. Ask your doctor about side effects.
This medicine may worsen your thinking or reaction. Be careful if you are driving or doing something that requires attention from you.
Avoid exposure to sunlight or tanning beds. Bicalutamide can make you more sensitive to the sun. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outside.
This medicine can get into body fluids (urine, feces, vomiting). Carers should wear rubber gloves when caring for the patient, when handling dirty underwear or changing diapers. Wash your hands before and after removing gloves. Wash dirty clothes and bed linens separately from the other.
Other drugs may interact with bicalutamide, including prescription and over-the-counter medications, vitamins and plant products. Tell each of your health care providers about all the medicines that you are using now, and about any medicine that you start or stop using.
Dosage of bicalutamide
Follow all directions on the recipe label. Your doctor may sometimes change your dose. Do not take this medicine in larger or smaller quantities or for longer than recommended.
Bicalutamide is usually taken once a day in the morning or in the evening. You can take the medicine with or without food. Try to take the medicine at the same time every day.
You should not stop using bicalutamide if your doctor does not tell you about it.
When using bicalutamide, you may need frequent blood tests
Store at room temperature away from moisture and heat.
Read all patient information, drug guides and instructions provided to you. If you have any questions, ask your doctor or pharmacist.
Take the missed dose as soon as you remember. Leave it if it’s time for the next scheduled dose. Do not take additional medication to make up for the missed dose.