Bisoprolol is the general name for the branded preparation of Zebet, which is used to treat high blood pressure.
The drug is also sometimes used to treat heart failure.
Bisoprolol belongs to a class of drugs called beta-blockers. It works by relaxing the blood vessels, slowing the heart rate and reducing the contractility of the heart.
The drug can be used alone or with other medicines. Often people who take this drug also lead a healthy lifestyle to control their blood pressure.
The US Food and Drug Administration (FDA) first approved bisoprolol in 1992. It is available as Zebeta from Duramed Pharmaceuticals.
Before taking bisoprolol, tell your doctor if you have or have ever had:
- Diseases such as asthma, chronic bronchitis or emphysema
- Heart failure, heart disease, slow heart rate or any other heart disease
- Circulation problems
- Sick thyroid gland
- Liver disease
- Kidney disease
- Mental illness, such as depression
If you are allergic, you should know that bisoprolol can worsen your allergic reactions. Talk with your doctor if that’s what’s bothering you.
If you have diabetes, bisoprolol may make it difficult to recognize the symptoms of hypoglycemia (low blood glucose). Discuss this effect with your doctor.
Let your health care provider know that you are taking bisoprolol before any surgery, including dental procedures.
Your doctor will closely monitor your condition while you are taking Bisoprolol.
Your doctor can advise you on certain diets and lifestyle changes, while taking Bisoprolol. Follow these instructions carefully.
Bisoprolol helps to control high blood pressure, but it will not cure this condition. Continue to take medicine even if you feel well.
Do not stop taking Bisoprolol without first talking to your doctor. Your doctor will gradually reduce the dose for taking the drug.
Pregnancy and Bisoprolol
It is not known whether bisoprolol can harm an unborn baby yet.
Tell your doctor if you are pregnant or can become pregnant while taking medicine.
It is also unknown whether bisoprolol passes into breast milk and can harm the baby. Talk with your doctor before breastfeeding.
Bisoprolol: side effects
Common side effects
Tell your doctor if any of the following side effects become serious or persistent:
- Increased frequency of urination
- Dry mouth
- Mild itching
- Weak joint or muscle pains
- Depression or anxiety
- Loss of interest in sex
Serious side effects
Immediately notify your doctor if you experience the following serious side effects:
- Swelling of the hands, feet, ankles or legs
- Unusual weight gain
- Inconsistent Breath
- Rare or rapid heart rate
- Thoracic pain
- Painful urination
- Numbness, tingling, or a feeling of coldness in the hands and feet
- Symptoms of an allergic reaction (may include hives, rash, itching, chest tightness, or swelling of the face, lips, tongue, or throat)
Tell your doctor about all prescription and over-the-counter, illegal, recreational, herbal, dietary or dietary preparations that you are taking, especially:
- Calcium channel blockers, such as Diltiazem (Cardizem, Cartia XT, Dilacor XR or Tiazac), Verapamil (Calan, Covera-HS or Verelan) or Tarka (Trandolapril and Verapamil)
- Catapres or Kapvay (Clonidine) or Clorpres (Clonidine and Chlorthalidone)
- Golenya (fingolimod)
- Medications such as Albuterol (Ventolin or Proventil), Tornalate (Bitolterol), Alupent (Metaproterenol), Maxair (Pirbuterol) or Terbutaline (Brethaire, Brethine or Bricanyl)
- Drugs for diabetes (including insulin)
- Medications such as Norpace (Disopyramide)
- Other beta blockers, such as Tenormin (Atenolol), Coreg (Carvedilol), Normodyne or Trandate (Labetalol), Lopressor or Toprol (Metoprolol), Corgard (Nadolol), Inderal or InnoPran (Propranolol) or Betapace (Sotalol)
- Rifadine or Rimfantin (Rifampin), Reefater (Rifampin, Isoniazid and Pyrazinamide) or Rifamate (Rifampin and Isoniazid)
Bisoprolol and other interactions
Bisoprolol may cause you drowsiness.
Do not drive or do any other activity that requires vigilance until you know how this medicine affects you.
Bisoprolol and alcohol
Alcohol can worsen certain side effects of bisoprolol.
Talk to your doctor before drinking alcohol while taking this medicine.
Dosage of Bisoprolol
Bisoprolol is supplied as a tablet, which must be taken orally. This is usually done once a day.
Take Bisoprolol with a full glass of water and try to use the medicine at about the same time every day.
Your dose will be based on your medical condition and response to treatment.
Follow the instructions on the label carefully. Do not take more or less Bisoprolol than recommended.
Your doctor will probably start with a low dose of bisoprolol and gradually increase it.
Overdose of bisoprolol
Symptoms of an overdose of bisoprolol may include:
- Wheezing or shortness of breath
- Slow pulse
- Pale skin
If you suspect an overdose, immediately contact a poison control center or an emergency room.
You can contact the Toxicology Center
The missed dose of Bisoprolol
If you miss a dose of Bisoprolol, take it as soon as you remember.
But if it’s time for the next scheduled dose, skip it and continue with your usual schedule of taking medications.
Do not take additional medication to make up for the missed dose.