Budesonide is the generic name of a prescription drug that is sold under the trademarks of Entocort EC, Uceris, Pulmicort, PulmicortFlexhaler, PulmicortRespules and Rhinocort.
Budesonide refers to a variety of conditions, including bowel disease, such as Crohn’s disease and ulcerative colitis, lung diseases such as asthma and chronic obstructive pulmonary disease (COPD), and allergic rhinitis (hay fever)
It is also one of the drugs found in the Symbicort inhaler, which is used to treat COPD and asthma.
Budesonide was approved in 1994 by the Food and Drug Administration (FDA) under the trademark Rhinocort and was manufactured by AstraZeneca.
You should not take budesonide if you are allergic to it or any of its ingredients, or if they have one of the following conditions:
- High blood pressure or congestive heart failure (CHF)
- Problems with the liver
- Eye conditions such as glaucoma or cataracts
- Current infection
- Mental or mood problems
In addition, it is important to note that children should not take prolonged-release (CP) or long-acting capsules.
Talk to your doctor before taking budesonide if you:
- Take Budesonide with a delayed release and are going to perform an operation
- If you have osteoporosis
- Problems with immunity
Pregnancy and Budesonide
Budesonide, which is taken by mouth, can harm a developing fetus.
Inspired budesonide forms are classified as Category B Pregnancy, which means that it is unlikely to harm a developing fetus.
Regardless, you should tell your doctor if you are pregnant or plan to become pregnant before taking this medication.
Budesonide enters the breast milk. Talk with your doctor if you are breast-feeding or planning to breast-feed before or after taking Budesonide.
Budesonide for dogs and cats
Studies show that budesonide works just as well as prednisone for the treatment of inflammatory bowel disease in dogs.
Budesonide is also prescribed for cats suffering from inflammatory bowel disease (IBD) because it not only helps alleviate their symptoms, but also has fewer side effects than other steroid treatments.
Bodezonide: side effects
- Nausea, vomiting, diarrhea and constipation
- Dizziness and headache
- Violation of the stomach or stomach pain, gas and bloating
- General or joint pain
- Low level of potassium in the blood
- Weakened immune system
- Infection of the bladder or kidneys
Serious side effects of budesonide:
- Cushing’s syndrome (more likely with long-term use)
- Decreased adrenal function (more likely, with long-term use and higher doses)
- Pressure in the space between the skull and the brain
- A life-threatening allergic reaction called anaphylaxis
It is always important to share with your doctor and pharmacist all the medicines that you take.
You should not take Budesonide if you take the following drugs:
- Theracrys (BCG live)
- Medications for viruses such as Norvir (ritonavir) or Incivek (telaprevir)
- Diabetic medications such as Betta or Bydureon (exenatide), Preza (acarbose), Amaryl (glimepiride), Diabetes or Glinase (glyburide), and Glucotrol or Glucotrol XL (glipizide)
- Diuretics such as Microniside or Zide (hydrochlorothiazide), bumetanide, diurel (chlorothiazide), Edecrine (ethacrynic acid), and Zaroxoline (metalazone)
- Cordarone, Pacerone or Nexterone (amiodarone) or Multaq (dronedarone)
Budesonide and alcohol
Because budesonide and alcohol can cause dizziness, taking two together can worsen this effect.
You should avoid drinking while taking this drug.
Budesonide and grapefruit juice
You should avoid eating grapefruit and its juice when taking budesonide.
Grapefruit juice slows the body’s ability to destroy Budesonide, which can lead to an increase in the level of the drug in the blood.
Budesonide is available in the form of tablets, nasal spray, suppository and for inhalation in the form of dry powder or aerosol and liquid formulations (for use with nebulizer).
Doses vary depending on the brand and dosage form.
If you are taking budesonide Entercort EC from Crohn’s disease, the usual dose is 9 mg orally every morning for up to 8 weeks.
The Uceris brand is available in two different forms: sustained-release tablets and foam. Both are used to treat ulcerative colitis.
The usual dose for sustained release tablets is 9 mg by mouth every morning for 8 weeks.
Foam Uceris, which is 2 mg per dose, should be used twice a day for the first 2 weeks, then once a day right before bedtime for the last 4 weeks.
Pulmicort Flexhaler for asthma is supplied in doses of 90 μg and 180 μg for inhalation.
Your doctor will work with you to find out how much medicine you need and how often you need to use it.
You should not take more than 1440 mcg of this medication in a single day.
Pulmicort Respules have 0.25 mg, 0.5 mg and 1 mg. Dosages vary from 0.5 mg once a day to 0.25 mg twice daily.
Overdose of budesonide
If you suspect an overdose, you should immediately contact a toxicology center or an emergency room.
Missed dose of budesonide
If you miss a dose of Budesonide, try to take it as soon as you remember.
If it’s time for the next dose, skip not and take the next dose in regular time.
Do not take two doses of the medication at the same time.