Cefuroxime is a prescription medication available under the trade names Ceftin and Zinacef.
It is an antibiotic used to treat certain infections caused by bacteria.
Cefuroxime was originally approved by the Food and Drug Administration (FDA) under the trademark Ceftin, manufactured by GlaxoSmithKline, in 1987.
You should not take Cefuroxime if you:
- You are allergic to Cefuroxime or any other ingredients contained in the preparation
- Accept Theracrys
Talk with your doctor before taking Cefuroxime, if you:
- Allergy to penicillin
- Allergies to other antibiotics, such as ceflacore, cefdinir, ceflex (cephalexin), or antibiotics in cephalosporin
- Problems with kidney or liver
- Suffer from malnutrition
- Recently had either an infection, or an inflammation of the intestine during or after taking antibiotics
Cefuroxime can reduce the effectiveness of contraceptives (pills, patches or injections).
You may need to use a reserve form of contraception while taking Cefuroxime.
Pregnancy and Cefuroxime
Cefuroxime is safe for your unborn child.
Regardless, you should tell your doctor if you are pregnant or plan to become pregnant before taking this medication.
Cefuroxime is absorbed into breast milk. Tell your doctor if you are feeding or plan to breast-feed before taking this medication.
Side effects of cefuroxime
- Nausea, vomiting and diarrhea
- Kidney problems
- Allergic reaction
Serious side effects:
- A life-threatening allergic reaction, called anaphylaxis
- Edema of the face, including the eyes, lips, mouth, tongue and throat
- Severe and possibly life-threatening skin reactions, such as Stephen-Johnson syndrome or toxic epidermal necrolysis (TENs)
- Blood disorders, such as low platelet counts or low levels of all blood cells
- Low white blood cell count
- Severe form of diarrhea, marked by a loose, watery stool and unpleasant odor
Always share with your doctor and pharmacist all the medicines that you take.
This includes prescription and over-the-counter (OTC) medicines, supplements such as vitamins and other nutritional supplements (nourishing cocktails, protein powders, etc.), herbs and any illegal or recreational drugs.
You should not take Cefuroxime if you are taking Theracrys (BCG liveintravesical)
Some other drugs that have severe interactions with cefuroxime include:
- Acid reflux drugs, such as Tagamet (cimetidine), Dexilant (deslansoprazole), and Aciphex (rabeprazole)
- Other acid reflux drugs, such as Pepsid (famotidine), Zantac (ranitidine), and Osid (nizatidine)
- Vivotif (vaccine)
- Aluminum hydroxide, calcium carbonate, magnesium hydroxide, sodium bicarbonate
- Cellcept (mycophenolate mofetil) and Myfortic (mycophenolic acid)
Cefuroxime and alcohol
You should avoid or limit alcohol consumption when taking Cefuroxime.
Cefuroxime and grapefruit juice
You should avoid eating grapefruit and drinking its juice while taking Cefuroxime.
Grapefruit juice slows down the process when the body is able to destroy Cefuroxime, which can lead to an increase in its level in the blood.
Dosage of cefuroxime
Cefuroxime is supplied in tablets of 250 mg and 500 mg.
Doses usually range from 250 mg twice daily to 500 mg twice daily for a period of 5-10 days for most infections.
Symptoms of Lyme disease can be treated up to 20 days.
With gonorrhea, your doctor may prescribe a single dose of 1000 mg.
It is very important to take Cefuroxime exactly as prescribed by the doctor.
Otherwise, the infection can return and become much more difficult to treat.
Overdose of Cefuroxime
If you suspect an overdose of Cefuroxime, you should immediately contact a toxicology center or an emergency room.
The missed dose of Cefuroxime
If you miss a dose, try to accept it as soon as you remember.
If it’s time for the next dose, skip it and take the next dose in regular time.
Do not take two doses of the medication at the same time.