Flutamide is an antiandrogen. It works in the body to prevent the action of androgens (male hormones).
Flutamide is used together with another hormone to treat prostate cancer.
Flutamide can also be used for purposes not listed in this medication guide.
Flutamide can cause serious problems with the liver. Immediately call your doctor if you have stomach pain, itching, fatigue, loss of appetite, dark urine, clayey stools or jaundice (yellowing of the skin or eyes).
You will need frequent blood tests to check your liver function while you are taking flutamide.
You should not use this medicine if you are allergic to flutamide.
Flutamide should never be taken by women and children.
Although flutamide is not used by women, this medicine can cause birth defects if the woman is exposed to it during pregnancy.
To ensure that flutamide is safe for you, tell your doctor if you have:
- liver disease;
- deficiency of the genetic enzyme, called deficiency of glucose-6-phosphate dehydrogenase (G6PD)
- hemoglobin M disease;
- if you smoke;
- if you take a blood thinner (warfarin, coumadin, gentenes).
Flutamide: side effects
Obtain immediate medical attention if you have signs of an allergic reaction: shortness of breath; swelling of the face, lips, tongue, or throat.
Flutamide can cause serious problems with the liver. Call your doctor right away if you have:
- nausea, pain in the stomach, loss of appetite;
- itching, fatigue, flu symptoms;
- dark urine, clayey stool;
- jaundice (yellowing of the skin or eyes).
Common side effects may include:
- breast tumor;
- vomiting, diarrhea;
- impotence, loss of interest in sex.
This is not a complete list of side effects and others may also occur. Ask your doctor about side effects.
To prevent diarrhea, avoid using dairy products such as milk, cheese and yogurt. Do not use laxatives while taking flutamide.
This medicine can pass in body fluids (urine, feces, vomiting). Carers should wear rubber gloves when caring for the patient. Wash your hands before and after removing gloves. Wash contaminated clothing and bedding separately from other laundry.
Other drugs may interact with flutamide, including prescription and non-prescription drugs, vitamins and plant products. Tell each of your health care providers about all the medicines that you are using now, and about any medicine that you start or stop using.
Follow all directions on the recipe label. Do not take this medicine in large or small quantities, or longer than recommended.
Flutamide is usually taken every 8 hours. Follow the instructions of your doctor.
Call your doctor if you have severe or persistent diarrhea. Your doctor can recommend a medicine for diarrhea.
Drink plenty of fluids while you are taking flutamide. Your doctor may recommend a special diet to help prevent diarrhea.
When using flutamide, you may need frequent blood tests.
You should not stop using flutamide suddenly. Sudden discontinuation may worsen your condition.
Store at room temperature away from moisture, heat and light.
Read all the information, medication guides and instructions provided to you. If you have any questions, ask your doctor or pharmacist.
Take the missed dose as soon as you remember. Skip it if it’s time to take the next scheduled dose. Do not take additional medication to make up for the missed dose.
Call your doctor for instructions if you miss the appointment for an LHRH injection.