Letrozole, sold under the trademark Femara, is a prescription drug used to treat advanced breast cancer, as well as in women who have had menopause.
Doctors can use Letrozole without a prescription to treat infertility to help stimulate ovulation in women.
Initially manufactured by Novartis, the Food and Drug Administration (FDA) first approved Femara in 1997.
You should not take Letrozole if you:
- You are allergic to letrozole or any of its active or inactive ingredients
- Has not yet come the menopause
- Problems with the liver
Ask your doctor about Letrozole if you have glaucoma or other problems with increased pressure in the eye.
Letrozole: side effects
You should tell your doctor if any of the following side effects is serious or does not disappear:
- Bone, joint and / or muscle pain
- Headache and nausea
- Sweating, coughing
- Labored breathing
- Problems with sleep
- Weight gain
- High cholesterol
- Modified liver function tests
- Hair loss or alopecia
- Swelling of the ankles or feet
Serious side effects
You should stop using this medication and call your doctor if you experience the following serious side effects:
- Allergic reactions, including life-threatening allergic reactions
- Bone fragility and fractures of bones
- Heart attack, stroke and high blood pressure
- Uterine cancer
You must tell your doctor about all the medications that you take.
Do not take Letrozole if you are taking the following drugs:
- Contraceptive pills or go through therapy that uses estrogen
- Norinil (Mestranol)
- Soltamox (Tamoxifen)
Letrozole and alcohol
Both Letrozole and alcohol can cause headaches and nausea, and these side effects can worsen if you simultaneously use both drugs.
If possible, try to avoid or limit alcohol use when taking Lethrosol.
Letrozole and grapefruit juice
You should avoid the use of grapefruit and the use of its juice during the intake of letrozole.
Grapefruit juice slows down the process of destruction of Lethrosol, which can lead to an increase in its level in the blood.
Letrozole is supplied in tablets of 2.5 milligrams (mg).
To treat cancer, the usual dose is 2.5 mg per day.
If you are taking letrozole for infertility, your doctor can tell you to take either 2.5 mg or 5 mg of the drug, starting on the third day of your period for five days.
If you think you can overdose, immediately go to the emergency room or toxicology center.
Missed dose of Letrozole
If you miss the dose of letrozole, try to take it as soon as you remember.
However, if the next dose comes, skip it and continue with your usual dosing schedule.
Do not take an extra dose to make up for the missed one.