Piroxicam is the general form of the proprietary drug Feldene, an anti-inflammatory drug used to relieve pain, swelling, stiffness caused by arthritis.
Prescription medication can be used for various types of arthritis, including osteoarthritis, rheumatoid arthritis, gout and ankylosing spondylitis.
Piroxicam is also sometimes used to relieve pain caused by menstrual cramps, surgical operations, or childbirth.
The drug belongs to a class of drugs known as non-steroidal anti-inflammatory drugs (NSAIDs). It works by stopping certain substances in the body that can cause inflammation.
The Food and Drug Administration (FDA) approved piroxicam in 1982. It is produced as Feldene by Pfizer, Inc.
Piroxicam may increase the risk of heart attack in certain people.
This risk may be greater if you already have heart problems or you have been taking piroxicam for a long time.
Tell your doctor if you or any of your family members have or have ever had:
- Heart disease
- Heart attack
- High blood pressure
- High cholesterol
Do not take piroxicam directly before or immediately after cardiac bypass surgery.
Get immediate medical attention immediately if you experience any of the following symptoms when taking piroxicam:
- Inconsistent Breath
- Thoracic pain
- Weakness on one side of your body
- Slurred speech
This medicine may also increase the risk of stomach ulcers and bleeding. These problems can be serious, and sometimes fatal.
Older people and those taking NSAIDs, such as piroxicam, have a greater risk of developing intestinal problems for a long time. Alcohol consumption can also increase the risk of gastric bleeding or ulcers.
Tell your doctor before you start taking a pyroxycam if you are taking any of the following medicines:
- Anticoagulants (blood thinners), such as warfarin (Coumadin, Jantoven)
- Other NSAIDs, such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn)
- Oral steroids, such as dexamethasone (Decadron, Dexon), methylprednisolone (Medrol), and prednisone (Deltazone)
Also, let your health care provider know if you have ever had ulcers, stomach bleeding, gastritis, or any problems with bleeding.
Stop taking piroxicam immediately and call your doctor if you are experiencing:
- Stomach ache
- Vomiting, similar to the coffee grounds
- Bloody stools
- Black and resinous stools
Before taking piroxicam, you should tell your doctor if you have or have ever had:
- Nasal polyps
- Swelling of the hands, feet, ankles or legs
- Liver disease
- Kidney disease
- Bleeding of the stomach or intestines
- Low level of sodium in the blood
- History of alcohol abuse
- Allergy to medicines
Discuss the risks and benefits of using this medication with your doctor if you are over 65 years old. Older people often have serious side effects.
Piroxicam will help control your symptoms, but it will not cure your condition. It may take up to 12 weeks before you will enjoy all the benefits of this medication.
Tell your doctor that you are taking piroxicam before any type of surgery, including dental procedures.
Pregnancy and piroxicam
Piroxicam can harm an unborn child. Do not take this medication without talking to your doctor if you are pregnant or plan to become pregnant.
You should not especially take piroxicam during the last three months of pregnancy.
The medicine is found in breast milk and can harm an infant. Do not take piroxicam while breastfeeding.
Piroxicam for dogs
Piroxicam is commonly used to treat pain in dogs.
It can also be combined with other drugs to treat bladder cancer in dogs.
The medicine may have risks, so you should talk with your veterinarian before giving the piroxicam to the pet.
Side effects of piroxicam
Tell your doctor if any of the following side effects is serious or does not disappear:
- Diarrhea or constipation
Serious side effects of piroxicam
Immediately notify your doctor if you experience any of the symptoms listed in the warning section above, or any of the following serious side effects:
- Eye problems
- Unexplained weight gain
- Joint Pain
- Rash, itching, or urticaria
- Difficulty breathing or swallowing
- Swelling of the face, eyes, lips, tongue, throat, hands, feet, ankles
- Pale skin
- Excessive fatigue or lack of energy
- Rapid heartbeat
- Unusual bleeding or bruising
- Stomach upset
- Loss of appetite
- Pain in the upper right side of the stomach
- Symptoms of influenza
- Yellowing of eyes or skin
- Difficult or painful urination
- Discolored or bloody urine
Tell your doctor about all the medicines that you take, especially those listed in the warnings section above, or any of the following:
- Angiotensin converting enzyme (ACE) inhibitors such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril) , ramipril (Altace) and trandolapril (Mavik)
- Lithium (Eskalith, Lithobid)
- Medications for Diabetes
- Methotrexate (Rheumatrex)
- Phenytoin (Dilantin)
Piroxicam and other interactions
Piroxicam may cause dizziness or drowsiness.
Do not drive until you know how this drug affects you.
Piroxicam and alcohol, tobacco
Alcohol consumption or use of tobacco products may increase the risk of serious side effects when taking piroxicam.
Talk with your doctor about these potential interactions.
Dosage of Pyroxicam
Piroxicam is supplied as a tablet for oral administration. Usually this is done once or twice a day.
Take this medicine at about the same time each day with a full glass of water.
You can take piroxicam with food if the reception upsets your stomach.
Follow the instructions on the label carefully. Do not take more or less piroxicam than your doctor recommends.
Piroxicam: an overdose
Symptoms of overdose may include:
- Stomach upset
- Lack of energy
- Bloody, black or tarry stools
- Vomiting, similar to the coffee grounds
If you suspect an overdose, immediately contact a poison control center or an emergency room.
Missed dose of piroxicam
If you miss a dose of piroxicam, take it as soon as you remember.
However, if the next dose comes, skip it and continue your regular medication schedule.
Do not double the dose to make up the missed one.