Plavix is a form of brand name for the typical clopidogrel bisulfate drug, an antiplatelet drug that is used to prevent blood clots.
Blood clots can form in the blood as a result of certain conditions of the heart or blood vessels.
For example, Plavix is often prescribed after a heart attack or stroke.
Plavix is also provided to those who have unstable angina or peripheral artery disease.
Using Plavix in combination with aspirin may be more effective in preventing another heart attack, but this will increase the risk of bleeding.
In 1997, Plavix was sold to Bristol-MyersSquibb and Sanofi, and it was approved by the Food and Drug Administration (FDA).
Warnings by Plavix
Since Plavix is designed to keep platelets from coagulation and blood clots, this increases the likelihood that you can bleed, even if your injury is negligible.
It is important that your doctor perform blood tests before using this medication to make sure that you do not have any genetic conditions that will make it dangerous for you to take Plavix.
If you have a stomach ulcer or head trauma that caused bleeding in the brain, you should not use Plavix. If you are planning to perform surgical or dental treatment, make sure that your doctor knows that you are using Plavix long before the procedure.
Never use any medication, including Plavix, if you are not sure that you do not have any allergies to it. Talk to your doctor about any allergies that you may have with such medicines, such as prasugrel (Effient), ticagrelor (Brilinta) or ticlopidine (Ticlid), to make sure that Plavix is safe. Tell your doctor about any serious conditions that you may have, especially those associated with bleeding or blood clotting disorder.
Pregnancy and Plavix
Although Plavix, as you know, is not harmful to your fetus.
There is insufficient data on breastfeeding, so doctors advise not to breastfeed if you use Plavix.
Plavix for cats
It is known that Plavix helps reduce blood clots in cats.
Veterinarians prescribe it to help prevent thromboembolism of the cat’s aorta.
Talk with your veterinarian before giving your pet any medication, and closely follow your vet’s directions.
Side Effects of Plavix
- Pain in the head or joints
- Redness of the skin
- Taste problems
Stop taking Plavix and see a doctor if you experience the following serious side effects:
- Nose bleed
- Bloody or tarry stools
- Blood in the urine
- Coughing up blood
- Vomiting, similar to the coffee grounds
- Crushing pain in the chest that extends to the arm, shoulder or jaw
- Sudden numbness or weakness, especially on one side of your body
- Sudden headache
- Problems with vision, speech, or balance
- Purple or red spots under your skin
- Unusual bleeding in the mouth, vagina or rectum
Ask for emergency help if you find the following signs of an allergic reaction to Plavix:
- Labored breathing
- Swelling of the face, lips, tongue, or throat
Before you start taking Plavix, it is important that you provide your doctor with a complete list of all the drugs that you take, including vitamins and plant products, as they can interact with Plavix.
For example, the combination of Plavix with the following drugs may increase the risk of gastrointestinal and / or intestinal bleeding:
- Ibuprofen (Motrin, Advill, Nuprin)
- Naproksen (Narosin or Aleve)
- Etodolak (Lodin)
- Diclofenac (Cataflam or Voltaren)
- Indomethacin (indocin)
- Meloxicam (Mobic)
There are many other NSAIDs that can increase the risk of such problems with bleeding.
In 2009, the FDA warned of the pooling of Plavix with acid-containing products such as esomeprazole (Nexium) or omeprazole (Prilosec), as they could significantly reduce the effectiveness of the drug, as they inhibit the enzyme CYP 2C19, which activates Plavix.
These products are designed to reduce the acid content in the stomach.
Other drugs that inhibit this enzyme include:
- Cimetidine (Tagamet)
- Fluoxetine (Prozac, Sarafem and Symbyax)
- Fluvoxamine (Luvox)
- Ticlopidine (Tyclid)
- Fluconazole (Diflucan)
- Ketoconazole (Nizoral)
- Voriconazole (Vfend)
- Etravirine (Intelence)
In addition to avoiding drugs or products that interact with Plavix, it is important to avoid actions that can lead to bleeding or trauma.
You also need to be careful when shaving or brushing your teeth. Try not to drink alcohol, as this can also increase the risk of gastric or intestinal bleeding.
Most people take Plavix once a day.
Take the drug with food and plenty of water to reduce side effects.
Never stop taking Plavix without talking to your doctor about it.
Most people with unstable angina or a heart attack begin with a dose of 300 mg, then 75 mg once a day, along with 75-325 mg of aspirin. If you have a peripheral artery disease or a recent stroke, your doctor will probably prescribe a dose of 75 mg per day.
Never take more Plavix than your doctor prescribed.
If you are worried that you or someone else may have taken a lot of medication, call the emergency room right away or call the toxicology center.
Missed dose of Plavix
If you forget to take the medicine, take it as soon as you remember, if it’s not time for the next dose. If it’s time for the next dose, skip it and start a regular dosing schedule. Do not take additional pills to make up for the missed dose, unless your doctor advises you to do so.