Prednisolone is a prescription drug sold under the trademark Orapred, among other names.
It is used to treat various conditions, including:
- Asthma and other breathing disorders
- Skin Problems
- Ulcerative colitis (chronic, inflammatory bowel disease)
- Kidney problems
- Lupus (an autoimmune disease characterized by inflammation and various symptoms)
- Psoriasis (skin condition)
- Multiple sclerosis (a disease that causes weakness, numbness, loss of coordination and other problems, because the nerves in the body do not function properly)
- Problems with the adrenal glands
- Eye Conditions
- Problems with blood or bone marrow
Prednisolone is a corticosteroid. It works by stopping the release of substances in the body that cause inflammation.
The Food and Drug Administration (FDA) approved prednisolone for the first time in 1955. It is sold by various pharmaceutical companies.
Warnings of prednisolone
Steroid medications, such as prednisolone, can weaken your immune system. This can make you more prone to infection, or it can worsen an existing infection.
Be sure to tell your doctor about any illness or infection that you recently had before you start with prednisolone. You should not take this medicine if you have a fungal infection anywhere in your body.
Try to avoid people who are sick or have an infection while you are taking this medication.
Tell your doctor if you are exposed to chicken pox or measles while taking prednisolone.
Do not do any inoculations with this medication without first talking to your doctor.
Avoid those who have recently made “live” viral vaccines. These include measles, mumps and rubella (MMR), Bacillus Calmette-Guérin (BCG), oral poliomyelitis, rotavirus, smallpox, typhoid fever, yellow fever, chicken pox (chicken pox), shingles (shingles) and nasal flu vaccines (flu).
In addition, before taking Prednisolone, tell your doctor if you have or have ever had:
- Diseases of the liver or kidneys
- Thyroid problems
- Malaria (mosquito-borne disease caused by a parasite)
- Tuberculosis (TB, an infectious disease that mainly affects the lungs)
- Osteoporosis (a condition in which the bones become weak and brittle)
- Glaucoma or cataract (eye conditions)
- Herpes infection of the eyes
- Depression or other mental illness
- High blood pressure
- Myasthenia gravis (a neuromuscular disease that causes weakness)
- Chronic heart failure
- Adrenal Problems
- Stomach ulcer
- Ulcerative colitis (chronic inflammatory bowel disease)
- Diverticulitis (a digestive disease that inflames bags in the intestine)
- Allergy to any medicine
This medicine can cause changes in blood sugar levels. If you have diabetes, be sure to carefully monitor your condition.
Prednisolone may affect growth in children. Talk with your doctor if this causes concern.
Do not suddenly stop using prednisolone. You may experience unpleasant symptoms.
Talk with your doctor before stop taking this medication.
Tell any healthcare professional who treats you that you are taking prednisolone. This medicine may interfere with the results of certain laboratory tests.
If you use prednisolone for a long period of time, you may need to wear a medical label to warn or carry an identification card in case of an emergency.
Your doctor will probably want to monitor your condition by performing certain medical tests if you are taking prednisolone for a long time.
Pregnancy and Prednisolone
Prednisolone can harm an unborn child if it is taken during pregnancy.
Tell your doctor if you are pregnant or plan to become pregnant before using this medication.
Prednisolone passes into breast milk and can harm a child. Do not use this medication during breastfeeding without discussing it with your doctor.
Prednisolone side effects
Common side effects of prednisolone
Tell your doctor if any of the following side effects become serious or persistent:
- Dry or thinning skin
- Bruising or discoloration of the skin
- Mild nausea or abdominal pain
- Problems with sleep
- Mild mood changes
- Increased sweating
- Delayed wound healing
- Easy headache
- Increased appetite
- Weight gain
- Light Dizziness
- The menstrual period has changed
- Changes in the shape or location of fat in the body, especially in the area of the hands, feet, face, neck, chest or waist
Serious side effects of prednisolone
Immediately notify your doctor if you experience the following serious side effects:
- Eye problems
- Rapid weight gain
- Inconsistent Breath
- Unusual thoughts or behavior
- Irregular or severe heartbeat
- Thoracic pain
- Coughing up blood
- Bloody or tarry stools
- Symptoms of infection that may include fever, chills, sore throat, or coughing
- Symptoms of pancreatitis that may include severe pain in the upper stomach, which spreads to the back, nausea and vomiting, or rapid heartbeat
- Symptoms of low potassium, which may include confusion, severe thirst, irregular heart rhythm, increased urination, discomfort in the legs, muscle weakness or sensation of lameness
- Symptoms of dangerously high blood pressure, which may include severe headache, blurred vision, anxiety, buzzing in the ears, confusion, shortness of breath, chest pain or uneven heartbeat
- Symptoms of a severe allergic reaction, which may include hives, shortness of breath, chest tightness or swelling of the face, lips, tongue, or throat
Tell your doctor about all illegal, recreational, herbal, food or dietary preparations that you are taking, especially:
- Blood solvents such as Coumadin (Warfarin)
- Gengraf, Neoral or Sandimmune (Cyclosporine)
- Insulin or any other cure for diabetes
- Nizoral (ketoconazole)
- Rifadine, Reefater, Rifamate or Rimaktan (rifampin)
- Medications such as Dilantin (Phenytoin) or Solfoton (Phenobarbital)
- Oral contraceptives (birth control pills)
Prednisolone and alcohol
Drinking alcohol can increase the risk of developing gastric bleeding when using prednisolone.
Avoid drinking alcohol while taking this medication.
Prednisolone and other interactions
Prednisolone can make you dizzy.
Do not drive or do other actions that require vigilance until you know how this medicine affects you.
Prednisolone has various forms, including tablets, solutions, syrups, liquids, suspensions and disintegrating tablets.
Your dose will depend on your condition and response to treatment.
Follow the instructions of your doctor carefully. Do not take more or less Prednisolone than recommended.
Your doctor may change the dose of Prednisolone if you experience unusual stress or a serious illness.
Be sure to measure the liquid form of prednisolone with a special cup for measuring the dose (and not an ordinary spoon). Ask your pharmacist about this if you do not have a device for measuring the dose.
You may need to shake the liquid well before measuring the dose.
Do not remove the tablet from the blister pack until you are ready to take the medicine. Use dry hands when opening the package and tear off the foil – do not squeeze the tablet through the foil.
Let the dissolving tablet dissolve in the mouth, do not chew it. If necessary, you can drink some liquid.
Prednisolone: an overdose
If you suspect an overdose of Prednisolone, immediately contact a poison control center or an emergency room.
You can contact the Toxicology Center
Missed dose of prednisolone
Ask your doctor to tell you what to do if you miss a dose of prednisolone.