Torsemide is the generic name for the proprietary Demadex drug used to treat high blood pressure and swelling caused by heart disease, kidneys, or liver disease.
Prescription medicine refers to a class of drugs called diuretics. It works by helping the kidneys eliminate excess water and salt from the body, producing more urine.
The Food and Drug Administration (FDA) approved torsemide in 1993. It is produced as Demadex by Roche Pharmaceuticals.
Before taking torsemide, tell your doctor if you have or have ever had:
- Fluid in the abdominal cavity
- Hearing problems
- Problems with urination
- High levels of uric acid in the blood
- Blood disorder
- Kidney disease
- Heart attack or heart failure
- Liver disease
- Allergy to medicines
Too much torsemide can lead to serious loss of water and minerals. Be sure to take this medicine exactly as prescribed by your doctor.
Your doctor will want to monitor your condition while you are taking this medicine. Be sure to continue all meetings with your doctor’s laboratory.
Tell your doctor if you are dehydrated before taking torsemide. This medicine can increase the risk of dehydration, so you may need to avoid intense physical activity and exposure to very hot weather.
Immediately notify your doctor if you experience:
- Strong thirst
- Dry mouth
- Muscle cramps or weakness
The drug can affect the level of glucose in the blood. If you have diabetes, be sure to carefully monitor your blood glucose and contact your healthcare provider before you change the dose of your diabetes medication.
Torsemide should not be given to children, because safety and efficacy in this age group are not confirmed.
Elderly people may be more sensitive to certain side effects of torsemide. Talk with your doctor about this problem if you are over 65 years old.
Be sure to tell your health care provider that you are taking torsemide before performing any surgery, including a dental procedure.
Your doctor can tell you to take a potassium supplement while you are taking turmidine. Follow these instructions carefully.
Torsemide can make your skin more sensitive to sunlight. Avoid unnecessary exposure to sun, sun and sunburn. Spread sunscreen or wear protective clothing outdoors.
Continue taking torsemide even if you are feeling well. Do not stop taking the medicine before talking to your doctor.
Pregnancy and torsemide
Torsemide is not considered harmful to the fetus. However, talk to your doctor before taking this medication, if you are pregnant or plan to become pregnant.
It is unknown whether the medicine passes into breast milk and whether it can damage the infant. Talk with your doctor before taking this medicine if you are breast-feeding a baby.
Side effects of torsemide
Tell your doctor if any of the following side effects become serious or persistent:
- Excessive urination
- Nasal inflammation
Serious side effects of torsemide
Immediately notify your doctor if you experience any of the symptoms listed in the “Alerts” section above, or any of the following serious side effects:
- Thoracic pain
- Fast or irregular heartbeat
- Symptoms of an allergic reaction (may include hives, rash, itching, chest tightness, or swelling of the face, lips, tongue, or throat)
- Fever, chills, or sore throat that does not disappear
- Hearing loss or ringing in the ears
- Loss of appetite or rapid weight loss
- Red, swollen skin
- Unusual bleeding or bruising
- Pain that begins in the stomach but can spread to the back
- Unusual weakness or fatigue
- Muscle spasms
- Rectal bleeding
- Vomiting with blood
Tell your doctor about all the medicines that you take, especially:
- Aminoglycoside antibiotics, such as Amikin (amikacin), Garamycin (gentamicin), or Bethesis or Tobi (tobramycin)
- Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) such as Advil or Motrin (ibuprofen) or Aleve (Naproxen)
- Corticosteroids such as Celestone, Entocort, Cortone, Decadron, Dexpak or Dexasone, Florinef, Cortef or Hydrocortone, Hydrolortisone, Rayos (prednisone) or Aristocort or Azmacort (triamcinolone)
- ACTH or HP ActharGel (corticotropin)
- Lanoxin (digoxin)
- Edecrine (ethacrynic acid)
- Indocin (indomethacin)
- Lithobid or Eskalith (lithium)
- Balanced (probenecid)
- Medications for high blood pressure or pain
In addition, if you are taking Questran (cholestyramine), take it four hours before or one hour after taking torsemide.
Torsemide and other interactions
Licorice and Korean (Asian) ginseng can interfere with how torsemide will work in your body. Avoid these foods while taking torsemide.
Torsemide may cause dizziness, fainting, or drowsiness. Do not drive or perform actions that require vigilance until you know how this medicine affects you.
Torsemide and alcohol
Alcohol can worsen certain side effects of torsemide. Avoid drinking alcohol while taking this medication.
Dosage of torsemide
Torsemide is supplied as a tablet. It is usually taken once a day, with or without food.
Try to take torsemide at about the same time every day.
Follow the instructions on the label carefully. Do not take more or less torsemide than your doctor recommends.
Torsemide can cause you to urinate more or more often when you start taking it. You can take it until 6 pm, so as not to disturb the night’s sleep.
Overdosage of torsemide
Symptoms of a torsemide overdose may include:
- Dry mouth
- Excessive urination, accompanied by a decrease in the amount of urine
- Fast or irregular heartbeat
- Muscle weakness or cramps
If you suspect an overdose, immediately contact a poison control center or an emergency room.
The missed dose of torsemide
If you miss the dosemorside, take it as soon as you remember.
But if it’s time for the next scheduled dose, skip it and continue with your usual schedule of taking medications.
Do not take additional medication to make up for the missed dose.