Zyvox is the trademark of linezolid, which is used to treat skin infections and infections in the blood.
It is also used for other types of infections, especially those that are resistant to certain medications.
Zyvox works by stopping the growth of susceptible Gram-positive bacteria.
The Food and Drug Administration (FDA) approved the drug in 2000. It is manufactured by Pfizer, Inc.
Before taking Zyvox, tell your doctor if you have or have had:
- Infection that lasts a long time
- Carcinoid Syndrome
- Problems with the immune system
- Tumor adrenal gland
- Kidney disease
- Liver disease
Many drugs can interact with Zyvox. You may need to stop using certain medications for up to five weeks before taking Zyvox.
It is important to inform your doctor if you are taking or have recently taken one of the following:
- Azilect (rasagiline), Eldepryl (selegiline), furoxone (furazolidone), Marplan (isocarboxazide), Nardil (phenelzine) and Parnate (tranylcypromine)
- Amerge (naratriptan), Axert (almotriptan), Frova (frovatriptan), sumatriptan, rizatriptan, eletriptan and Zomig (zolmitriptan)
- Celexa, fluoxetine, Sarafem, Symbyax, escitalopram, fluvox), paroxetine, vilazodonisertraline
- duloxetine, venlafaxine, and devenlafaxine
- Anaphranin (clomipramine), Asendin (amoxapine), Adapine or Sinequan, amitriptyline, Norpramine (desipramine), Aventil or Pamlor, Surmontil (trimipramine), imipramine and Vivactil (protriptyline)
Do not stop taking Zyvox or any of your other medicines without first talking to your doctor.
Be sure to tell your doctor that you are taking Zyvox before surgery of any type, including a dental procedure.
This medicine will treat only bacterial infections. It will not affect the common cold, or any other viral infection.
Antibiotics can cause diarrhea. Immediately notify your doctor if you experience diarrhea.
If you have phenylketonuria, a condition in which a special diet should be followed, you should be aware that the liquid form of Zyvox can contain phenylalanine. Talk with your doctor if that’s what’s bothering you.
Pregnancy and Zyvox
It is not known whether the drug will harm an unborn baby. Tell your doctor if you are pregnant or can become pregnant while taking this medication.
It is also unknown whether the drug passes into breast milk and whether it can affect breastfeeding. Talk with your doctor before breastfeeding, taking Zyvox.
Side Effects of Zyvox
Tell your doctor if any of the following side effects become serious or persistent:
- Easy diarrhea or vomiting
- Nausea or abdominal pain
- Difficulty falling asleep
- White spots in the mouth
- Change the color of your language
- Mild rash
Serious side effects of Zyvox
Immediately notify your doctor if you experience the following serious side effects:
- Symptoms of an allergic reaction that may include hives, rashes, itching, shortness of breath or swelling of the face, lips, tongue, or throat
- Fever, sore throat, cough, chills, or other signs of infection
- Blisters or scaling of the skin
- Loss of coordination
- Unusual bleeding or bruising
- Muscle pain or weakness
- Numbness or a feeling of coldness in the hands or feet
- Changes in vision
- Low levels of erythrocytes, leukocytes or platelets
Tell your doctor about all medications you use, especially those listed in the “Warnings” section, and any of the following:
- Adderall, Dexedrine, DextroStat
- Methylphenidate (Concerta, Metadate, Methylin,)
- Other antibiotics
- Luminal and solfoton
- Phenylpropanolamine (no longer available in the US)
- Dylantine, Fenitek
- Rifadine, Rimatan, Rifamate, Reefater
Zyvox and other interactions
You may have to stop eating foods or consuming beverages that contain a large amount of tyramine. Some of them include:
- Alcoholic beverages
- Some cheeses
- Sour cream
- Canned figs
- Soy sauce
- Sausage and dried meat products
Talk with your doctor about what foods should be restricted or avoided while taking Zyvox.
Zyvox is available as a tablet, liquid or injection form.
Your dose and duration of treatment will depend on the type of infection, your weight and response to therapy.
Carefully follow the recipe instructions by taking Zyvox. Do not use more or less medicine than recommended.
Oral forms of Zyvox are usually taken twice daily for 10-28 days. Children under 11 years of age usually take the drug three times a day.
You can take an oral medication with or without food.
If you get an injection form of Zyvox, you can be shown how to do an injection at home. Follow the instructions of your doctor carefully.
If you suspect an overdose, immediately contact a poison control center or an emergency room.
Missed dose of Zyvox
If you miss a dose of Zyvox, take it as soon as you remember. But skip it if it’s time to take the next scheduled dose.
Do not take additional medication to compensate for the missed dose.